SCHEMBL8439645

SCHEMBL8439645

CC(O)OC(C)Oc1ccccc1C(C)(C)c1ccccc1OC(C)OC(C)O

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
SLC6A4 P31645 1/20 0.32
PPARG P37231 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869591 0.85 MAPT (0.36) MAPTADRA2AADRA2BADRA2CSLC6A4
SCHEMBL7188759 0.76 LMNA (0.37) MAPTADRA2AADRA2BADRA2CPPARG
SCHEMBL28016358 0.76 ALDH1A1 (0.40) MAPTADRA2AADRA2BADRA2CSLC6A4
SCHEMBL8439647 0.76 ALDH1A1 (0.37) MAPTADRA2AADRA2BADRA2CPPARG
SCHEMBL5574257 0.74 MEN1 (0.35) ADRA2AADRA2CSLC6A4KMT2AALDH1A1
SCHEMBL8827188 0.74 MAPT (0.37) MAPTPPARGALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL5097398 0.73 ATM (0.33) MAPTPPARGTDP1ATM
SCHEMBL9694538 0.73 ALDH1A1 (0.52) MAPTSLC6A4ALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL11649137 0.72 ADRA2A (0.46) MAPTADRA2AADRA2BADRA2CKMT2A
SCHEMBL4649149 0.72 ATM (0.40) PPARGIRAK4KMT2AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952429-A A BLACK PHOTOCURABLE RESIN COMPOSITION IS OBTAINED BY MIXING UNDER HEATING A BLOCK- OR GRAFT-COPOLYMER WITH CARBON BLACK; IMPROVED PHOTOSENSITIVITY, INSULATING PROPERTY; FORMING A BLACK MATRIX PARTICULARLY IN A COLOR FILTER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-14 US disclosed
EP-0787777-A1 CARBON BLACK GRAFT POLYMER, PROCESS FOR THE PRODUCTION OF THE POLYMER AND USE THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 1997-08-06 EP disclosed
US-4876173-A BINDER OF ACRYLATED ESTER, (METH) ACRYLIC ACID COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1989-10-24 US disclosed