SCHEMBL8439766

SCHEMBL8439766

CCCCCN1C(=O)C=C(C)C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.55
FAAH O00519 5/20 0.55
PTGS1 P23219 3/20 0.55
PTGS2 P35354 3/20 0.55
ALDH1A1 P00352 4/20 0.44
ALDH2 P05091 1/20 0.44
ALDH3A1 P30838 1/20 0.44
CES1 P23141 2/20 0.42
CDC25A P30304 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 1/20 0.40
CNR2 P34972 3/20 0.39
CNR1 P21554 1/20 0.39
MAPT P10636 2/20 0.39
RAB9A P51151 2/20 0.39
HSP90AA1 P07900 1/20 0.39
TLR9 Q9NR96 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187582 0.98 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL5970312 0.98 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL8439722 0.98 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL8438883 0.98 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL4654369 0.98 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL18999087 0.98 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL7761775 0.94 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL8883684 0.92 MGLL (0.46) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL8443620 0.90 MGLL (0.48) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL8886884 0.90 MGLL (0.48) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109453167-A Maleimide class compound is preparing the application in Li Shiman protozoon insecticide 浙江工业大学 2019-03-12 CN disclosed
EP-0495544-B1 Process for the synthesis of citraconimides AKZO NOBEL NV (NL) 1999-04-07 EP disclosed
EP-0648240-A1 PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS Akzo Nobel N.V. (NL) 1995-04-19 EP disclosed
EP-0495545-B1 Citraconimide (co)polymers and curing with anionic catalyst AKZO NOBEL NV (NL) 1994-12-28 EP disclosed
WO-1994001485-A1 PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS AKZO NOBEL N.V. (NL) 1994-01-20 WO disclosed
US-5221717-A CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST AKZO N.V. (NL) 1993-06-22 US disclosed
EP-0495545-A1 Citraconimide (co)polymers and curing with anionic catalyst Akzo Nobel N.V. (NL) 1992-07-22 EP disclosed