Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.58 |
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439722 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL5970312 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL18999087 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL4654369 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL8438883 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL8439766 | 0.98 | MGLL (0.55) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL7761775 | 0.92 | MGLL (0.47) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL8885012 | 0.92 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL907802 | 0.92 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8443620 | 0.92 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189794-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2019-01-29 | — | — | US | disclosed |
| US-20180022713-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2018-01-25 | — | — | US | disclosed |
| US-20170267685-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-09-21 | — | — | US | disclosed |
| US-9695132-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2017-07-04 | — | — | US | disclosed |
| US-9676785-B2 | HCV protease inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2017-06-13 | — | — | US | disclosed |
| US-20170137463-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2017-05-18 | — | — | US | disclosed |
| EP-2402136-B1 | POWDER SLUSH MOLDING MACHINE AND POWDER SLUSH MOLDING METHOD | FAURECIA INNENRAUM SYS GMBH (DE) | 2016-05-18 | — | — | EP | disclosed |
| US-8814550-B2 | Powder slush molding machine and powder slush molding method | NAKATA COATING CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| CN-102292203-B | Powder slush molding machine and powder slush molding method | NAKATA COATING CO LTD | 2014-05-07 | — | — | CN | disclosed |
| EP-2402136-A1 | POWDER SLUSH MOLDING MACHINE AND POWDER SLUSH MOLDING METHOD | Nakata Coating Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-20110316184-A1 | Powder Slush Molding Machine and Powder Slush Molding Method | NAKATA COATING CO., LTD. (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137463-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | PEPD, CTRL, CTSC | MGLL 192/4885FAAH 706/4885PTGS1 2210/4885 |
| US-20170267685-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | PRKACA, PRKDC, AURKC | MGLL 2893/4885FAAH 3940/4885PTGS1 2292/4885 |
| US-10189794-B2 | Heteroaryl compounds and uses thereof | ABCG2, CYP3A43, CYP3A5 | MGLL 616/4885FAAH 1433/4885PTGS1 3720/4885 |
| US-20180022713-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | MGLL 616/4885FAAH 1433/4885PTGS1 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.