Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.58 |
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5970312 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL18999087 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL4654369 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL8438883 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL187582 | 1.00 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL8439766 | 0.98 | MGLL (0.55) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL7761775 | 0.92 | MGLL (0.47) | MGLLFAAHPTGS1PTGS2CES1 | |
| SCHEMBL8885012 | 0.92 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL907802 | 0.92 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8443620 | 0.92 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495544-B1 | Process for the synthesis of citraconimides | AKZO NOBEL NV (NL) | 1999-04-07 | — | — | EP | disclosed |
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| EP-0643847-A1 | ELECTROPHOTOGRAPHIC MATERIAL CONTAINING PARTICULAR PHTHALOCYANINES. | AGFA GEVAERT NV (BE) | 1995-03-22 | — | — | EP | disclosed |
| EP-0495545-B1 | Citraconimide (co)polymers and curing with anionic catalyst | AKZO NOBEL NV (NL) | 1994-12-28 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |
| WO-1993024865-A1 | ELECTROPHOTOGRAPHIC MATERIAL CONTAINING PARTICULAR PHTHALOCYANINES | AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) | 1993-12-09 | — | — | WO | disclosed |
| US-5221717-A | CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST | AKZO N.V. (NL) | 1993-06-22 | — | — | US | disclosed |
| EP-0495545-A1 | Citraconimide (co)polymers and curing with anionic catalyst | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |