Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441966 | 0.84 | ALDH1A1 (0.52) | MCL1RIPK2ALDH1A1MAPTHK1 | |
| SCHEMBL8441823 | 0.84 | MCL1 (0.39) | MCL1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL8441801 | 0.84 | ALDH1A1 (0.55) | MCL1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL8441806 | 0.83 | TAAR1 (0.54) | MCL1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL8441774 | 0.82 | TBXAS1 (0.39) | RIPK2 | |
| SCHEMBL8437945 | 0.82 | TBXAS1 (0.39) | RIPK2 | |
| SCHEMBL8441378 | 0.82 | MCL1 (0.47) | MCL1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL8438622 | 0.82 | TBXA2R (0.59) | MCL1POLBKMT2AMAPTMEN1 | |
| SCHEMBL8441413 | 0.81 | ALDH1A1 (0.58) | MCL1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL8438681 | 0.79 | CA1 (0.53) | POLBKMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |