Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441806 | 0.92 | TAAR1 (0.54) | ALDH1A1MAPTTBXA2RTBXAS1MCL1 | |
| SCHEMBL8441378 | 0.90 | MCL1 (0.47) | ALDH1A1MAPTTBXA2RTBXAS1MCL1 | |
| SCHEMBL8441801 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTTBXA2RTBXAS1MCL1 | |
| SCHEMBL8438622 | 0.90 | TBXA2R (0.59) | MAPTTBXA2RTBXAS1MCL1AKR1C3 | |
| SCHEMBL8438681 | 0.87 | CA1 (0.53) | ALDH1A1MAPTTBXA2RTBXAS1CA1 | |
| SCHEMBL8441413 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTTBXA2RTBXAS1MCL1 | |
| SCHEMBL8442601 | 0.87 | TAAR1 (0.52) | ALDH1A1MAPTTBXA2RTBXAS1MCL1 | |
| SCHEMBL8439860 | 0.84 | MCL1 (0.44) | ALDH1A1MAPTMCL1HKDC1RIPK2 | |
| SCHEMBL8438979 | 0.79 | TAAR1 (0.58) | ALDH1A1MAPTTBXA2RTBXAS1MCL1 | |
| SCHEMBL8437945 | 0.77 | TBXAS1 (0.39) | TBXA2RTBXAS1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |