SCHEMBL8439872

SCHEMBL8439872

CC(C)c1ccc(NC(=O)c2ccc(O)cc2O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 6/20 0.65
KLK1 P06870 4/20 0.65
KLK6 Q92876 4/20 0.65
ALOX15 P16050 1/20 0.57
POLB P06746 1/20 0.56
LMNA P02545 3/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GFER P55789 1/20 0.50
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CASP3 P42574 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28034382 0.91 PLG (0.73) PLGKLK1KLK6ALOX15POLB
SCHEMBL2270561 0.85 LMNA (0.68) PLGKLK1KLK6ALOX15LMNA
SCHEMBL8438123 0.83 NPC1 (0.66) PLGKLK1KLK6ALOX15POLB
SCHEMBL8439279 0.82 PNLIP (0.65) PLGKLK1KLK6ALOX15LMNA
SCHEMBL9081411 0.82 PLG (0.58) PLGKLK1KLK6POLBMAOA
SCHEMBL8405384 0.81 LMNA (0.69) PLGKLK1KLK6ALOX15POLB
SCHEMBL22799056 0.79 PLG (1.00) PLGKLK1KLK6KLKB1
SCHEMBL1096228 0.79 KMT2A (0.68) ALOX15POLBLMNACA12CA1
SCHEMBL2267515 0.79 KLKB1 (0.65) ALOX15LMNAALDH1A1GFERMAOA
SCHEMBL2272830 0.79 KLKB1 (0.69) ALOX15POLBALDH1A1MAOBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0756943-B1 Heat sensitive recording material NEW OJI PAPER CO LTD (JP) 1999-12-22 EP disclosed
US-5753588-A COMPRISING INDOLYLDIAZAPHTHALIDE BASIC DYE, DIPHENYL SULFONE OR BENZANILIDE DERIVATIVE COLOR ACCEPTOR NEW OJI PAPER COMPANY LIMITED (JP) 1998-05-19 US disclosed
EP-0756943-A1 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1997-02-05 EP disclosed