Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574263 | 0.87 | MAPT (0.40) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL8435951 | 0.85 | SMN1; SMN2 (0.37) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL9121007 | 0.83 | DPP8 (0.43) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL9121235 | 0.82 | DPP8 (0.44) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL9574226 | 0.82 | ATM (0.36) | MAPTRAB9AATMDPP8DPP9 | |
| SCHEMBL9121572 | 0.81 | DPP8 (0.44) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL9038821 | 0.80 | MAPT (0.41) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL9202870 | 0.80 | DPP8 (0.40) | MAPTCYP3A4CYP2C9TSHRRAB9A | |
| SCHEMBL9727854 | 0.80 | ALDH1A1 (0.42) | MAPTATMTDP1ALDH1A1HPGD | |
| SCHEMBL9208262 | 0.80 | ALDH1A1 (0.42) | MAPTATMTDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |