Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435951 | 0.91 | SMN1; SMN2 (0.37) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9574265 | 0.88 | DPP8 (0.40) | MAPTRAB9ADPP8DPP9NPC1 | |
| SCHEMBL8439876 | 0.87 | MAPT (0.38) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9202870 | 0.86 | DPP8 (0.40) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9121007 | 0.85 | DPP8 (0.43) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9574214 | 0.84 | DPP8 (0.35) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9574341 | 0.84 | DPP8 (0.35) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9121235 | 0.84 | DPP8 (0.44) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL8447430 | 0.84 | TPSAB1 (0.39) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL8444908 | 0.84 | TPSAB1 (0.39) | MAPTRAB9ACYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |