Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438726 | 0.80 | LMNA (0.43) | LMNAHTTMAPTTHRBKMT2A | |
| SCHEMBL8559241 | 0.75 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EMAPK1ADAMTS4 | |
| SCHEMBL8438814 | 0.74 | TBXA2R (0.56) | LMNAHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL8438812 | 0.73 | ALDH1A1 (0.48) | LMNAHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL10938219 | 0.72 | TSHR (0.58) | LMNAHTTKMT2AALDH1A1TSHR | |
| SCHEMBL10552330 | 0.70 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12953485 | 0.70 | ALDH1A1 (0.45) | LMNAKMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL767041 | 0.69 | TDP1 (0.55) | LMNAKMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16672960 | 0.69 | TSHR (0.55) | LMNAKMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16673023 | 0.69 | MAPT (0.62) | LMNAHTTMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |