Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559241 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8442525 | 0.76 | TBXA2R (0.52) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8441194 | 0.75 | TBXA2R (0.44) | ALDH1A1LMNATBXA2RMEN1HTT | |
| SCHEMBL8438125 | 0.73 | MMP2 (0.46) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8439894 | 0.73 | LMNA (0.44) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL17703607 | 0.71 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL9341770 | 0.70 | CYP1A2 (0.43) | PKMCA1CA2CA9CYP2C19 | |
| SCHEMBL8349568 | 0.70 | ALDH1A1 (0.79) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8438814 | 0.69 | TBXA2R (0.56) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL27759860 | 0.69 | SRC (0.47) | PKMCA1CA2CA9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |