Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | FADS1 | O60427 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202240 | 0.77 | MAOB (0.59) | MAOBFADS1RAB9ANPC1HPGD | |
| SCHEMBL8440621 | 0.74 | ALDH1A1 (0.52) | MAOBKMT2AMEN1MAPTTP53 | |
| SCHEMBL2761736 | 0.69 | CSNK2A2 (0.45) | MAOBKMT2AMEN1MAPTKDM4E | |
| SCHEMBL3788426 | 0.69 | NPC1 (0.76) | FADS1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15779338 | 0.68 | NPC1 (0.65) | FADS1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9524693 | 0.67 | FADS1 (0.58) | MAOBFADS1RAB9ANPC1KMT2A | |
| SCHEMBL27833865 | 0.67 | FADS1 (0.81) | MAOBFADS1RAB9ANPC1KMT2A | |
| SCHEMBL11869295 | 0.67 | SERPINE1 (0.57) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL2761993 | 0.67 | ALDH1A1 (0.48) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29555975 | 0.66 | MAPT (0.68) | FADS1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985912-A | COUMARONE COMPOUNDS AS BACTERICIDES | PFIZER INC. (US) | 1999-11-16 | — | — | US | disclosed |
| US-5624951-A | 4-hydroxy coumarin derivatives with antibacterial activity | PFIZER INC. (US) | 1997-04-29 | — | — | US | disclosed |