Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | FADS1 | O60427 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002342 | 0.91 | MAPT (0.73) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29556076 | 0.89 | RAB9A (0.68) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29556193 | 0.89 | MAPT (0.60) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29556244 | 0.89 | TP53 (0.55) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29555889 | 0.88 | MAPT (0.56) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL22103801 | 0.87 | TP53 (0.75) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29077780 | 0.84 | MEN1 (0.89) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29556162 | 0.84 | MEN1 (0.89) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL29556243 | 0.83 | TP53 (0.62) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL2682054 | 0.82 | KMT2A (1.00) | MAPTMEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |