Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613014 | 1.00 | ALDH1A1 (0.55) | ALDH1A1GAAMAOBHDAC4HDAC2 | |
| SCHEMBL6572244 | 0.83 | NPC1 (0.53) | ALDH1A1GAAHDAC4HDAC2HDAC8 | |
| SCHEMBL8440252 | 0.83 | NPC1 (0.61) | ALDH1A1GAANPC1CA12CA1 | |
| SCHEMBL29763172 | 0.83 | NPC1 (0.61) | ALDH1A1GAANPC1CA12CA1 | |
| Hydrochloric Acid SCHEMBL6786006 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAAHDAC4HDAC2HDAC8 | |
| SCHEMBL196223 | 0.81 | CA12 (0.68) | ALDH1A1HDAC4HDAC2HDAC8CA12 | |
| SCHEMBL11776866 | 0.79 | MAOB (0.57) | ALDH1A1GAAMAOBGABRA1GABRB2 | |
| SCHEMBL27700749 | 0.79 | ESR2 (0.59) | ALDH1A1GAAHDAC4HDAC2HDAC8 | |
| SCHEMBL581508 | 0.77 | TUBB4A (0.63) | ALDH1A1GAAMAOBNPC1CA12 | |
| SCHEMBL8940749 | 0.77 | HDAC4 (0.50) | ALDH1A1GAAHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0581777-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992017449-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |