SCHEMBL67498

SCHEMBL67498

COc1ccc(O)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
KDM4E B2RXH2 1/20 0.61
MEN1 O00255 1/20 0.61
GAA P10253 1/20 0.61
MAPT P10636 1/20 0.61
THRB P10828 1/20 0.61
RECQL P46063 1/20 0.61
BLM P54132 1/20 0.61
KMT2A Q03164 1/20 0.61
MCL1 Q07820 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
NQO2 P16083 1/20 0.61
RELA Q04206 1/20 0.61
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
CYP3A4 P08684 2/20 0.57
MAPK1 P28482 2/20 0.57
ERN1 O75460 1/20 0.57
TRIM24 O15164 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950410 1.00 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
Formaldehyde SCHEMBL8164524 0.93 NPC1 (0.59) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL340086 0.84 NPC1 (0.60) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL8440252 0.82 NPC1 (0.61) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL29763172 0.82 NPC1 (0.61) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL581508 0.80 TUBB4A (0.63) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL929945 0.80 CYP3A4 (0.56) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL172689 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL15086617 0.80 CYP1A2 (0.60) ALDH1A1SMN1; SMN2KDM4EMEN1GAA
SCHEMBL595280 0.80 MAOB (0.64) ALDH1A1SMN1; SMN2KDM4EMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117558791-B Light high-light-transmittance photovoltaic backboard and preparation method thereof 温州鑫泰新材料股份有限公司 2024-03-26 CN claimed
CN-117558791-A Light high-light-transmittance photovoltaic backboard and preparation method thereof 温州鑫泰新材料股份有限公司 2024-02-13 CN claimed
US-20230340180-A1 AROMATIC POLYOL-STABILIZED RESOL RESIN SAINT-GOBAIN ISOVER (FR) 2023-10-26 US claimed
EP-4172126-A1 AROMATIC POLYOL-STABILIZED RESOL RESIN SAINT-GOBAIN ISOVER (FR) 2023-05-03 EP claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-112457472-B Low-viscosity bio-based magnolol epoxy resin and preparation method thereof 广东工业大学 2022-10-04 CN claimed
CN-111995865-B Polymer material, preparation method thereof and manufacturing method of polymer product 湖南华曙高科技股份有限公司 2022-08-16 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
WO-2022003289-A1 AROMATIC POLYOL-STABILIZED RESOL RESIN SAINT-GOBAIN ISOVER (FR) 2022-01-06 WO claimed
CN-112625691-A Soil deodorant and preparation method and application thereof 浙江浙聚科技有限公司 2021-04-09 CN claimed
US-20160030437-A1 TAU AGGREGATION INHIBITOR NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) 2016-02-04 US claimed
EP-2962687-A1 TAU AGGREGATION INHIBITOR The Doshisha (JP) 2016-01-06 EP claimed
CN-104119921-A Etching paste composition and application thereof CHI MEI CORP 2014-10-29 CN claimed
US-7807740-B2 Two-component reaction resin and method of fastening using the resin HILTI AKTIENGESELLSCHAFT (LI) 2010-10-05 US claimed
US-20080171807-A1 Two-component reaction resin and method of fastening using the resin HILTI AKTIENGESELLSCHAFT (LI) 2008-07-17 US claimed
EP-1476549-B1 METHODS FOR TWO-DIMENSIONAL CONFORMATION-DEPENDENT SEPARATION OF NON-CIRCULAR NUCLEIC ACIDS LIFEIND EHF (IS) 2008-06-04 EP claimed
EP-0262061-B1 PROCESS FOR STABILIZING CHLORINATION MIXTURES OF PHENOL AND/OR CHLOROPHENOLS RHONE-POULENC CHIMIE (FR) 1993-02-24 EP claimed
US-4853153-A USING REDUCING AGENT AND CHLORINATED CYCLIC KETONE RHONE-POULENC CHIMIE (FR) 1989-08-01 US claimed
US-4746322-A Hair dye composition and process for using the same REPLIGEN CORPORATION (US) 1988-05-24 US claimed
US-3930862-A DYE DEVELOPER TRANSFER PHOTOSENSITIVE MATERIAL WITH SUBSTITUTED CATECHOL AUXILIARY DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160030437-A1 TAU AGGREGATION INHIBITOR MAPT, PSEN2, PSEN1 ALDH1A1 4120/4885SMN1; SMN2 202/4885KDM4E 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.