Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877775 | 0.82 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL7014701 | 0.80 | CLK4 (0.61) | NPC1RAB9ALTA4HTSHRGSTP1 | |
| SCHEMBL8407027 | 0.80 | LMNA (0.51) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL11485534 | 0.77 | LTA4H (0.48) | NPC1RAB9ALTA4HTSHRGSTP1 | |
| SCHEMBL2313930 | 0.76 | MEN1 (0.55) | NPC1RAB9ASMN1; SMN2LTA4HTSHR | |
| SCHEMBL27993361 | 0.76 | PARP10 (0.64) | SMN1; SMN2MEN1KMT2ASCN4A | |
| SCHEMBL5943091 | 0.76 | ALDH1A1 (0.64) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL16222829 | 0.75 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL5942714 | 0.74 | LTA4H (0.46) | RAB9AMCL1LTA4HTSHRMEN1 | |
| SCHEMBL21887691 | 0.74 | MAPK1 (0.58) | NPC1RAB9AMCL1LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872301-A | Bifunctional precursors for the preparation of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |