Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SGMS1 | Q86VZ5 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442526 | 0.91 | TBXA2R (0.57) | ALDH1A1GAASGMS1LMNACYP1A2 | |
| SCHEMBL8441480 | 0.88 | SGMS1 (0.56) | ALDH1A1GAASGMS1TBXA2RTBXAS1 | |
| SCHEMBL8442977 | 0.88 | SGMS1 (0.55) | ALDH1A1GAASGMS1CYP2C9TBXA2R | |
| SCHEMBL8437961 | 0.88 | MEN1 (0.54) | ALDH1A1GAASGMS1LMNACYP2C9 | |
| SCHEMBL8440903 | 0.87 | ALDH1A1 (0.62) | ALDH1A1SGMS1CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL8438768 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SGMS1LMNACYP2C9TBXA2R | |
| SCHEMBL8437798 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GAASGMS1LMNASMN1; SMN2 | |
| SCHEMBL8441006 | 0.84 | ALDH1A1 (0.43) | ALDH1A1GAASGMS1CYP1A2CYP3A4 | |
| SCHEMBL8438055 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAASGMS1LMNATAAR1 | |
| SCHEMBL8440911 | 0.81 | NAMPT (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |