Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HRAS | P01112 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442526 | 0.88 | TBXA2R (0.57) | ALDH1A1LMNAGAASMN1; SMN2NPSR1 | |
| SCHEMBL8442977 | 0.85 | SGMS1 (0.55) | ALDH1A1GAASGMS1 | |
| SCHEMBL8441480 | 0.85 | SGMS1 (0.56) | ALDH1A1GAASGMS1 | |
| SCHEMBL8437961 | 0.85 | MEN1 (0.54) | ALDH1A1LMNAGAANPSR1SGMS1 | |
| SCHEMBL8440588 | 0.85 | ALDH1A1 (0.60) | ALDH1A1LMNAGAASMN1; SMN2SGMS1 | |
| SCHEMBL8440903 | 0.84 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPSR1SGMS1 | |
| SCHEMBL7924104 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAGAASMN1; SMN2HRAS | |
| SCHEMBL8438768 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2SGMS1 | |
| SCHEMBL8439052 | 0.81 | VCAM1 (0.54) | ALDH1A1LMNANPSR1 | |
| SCHEMBL14712382 | 0.81 | NPSR1 (0.67) | ALDH1A1LMNAGAASMN1; SMN2HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |