Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442526 | 0.90 | TBXA2R (0.57) | ALDH1A1SGMS1PKMSMN1; SMN2MEN1 | |
| SCHEMBL8437961 | 0.89 | MEN1 (0.54) | ALDH1A1SGMS1MEN1KMT2AHTT | |
| SCHEMBL8441480 | 0.87 | SGMS1 (0.56) | ALDH1A1SGMS1MEN1KMT2AHTT | |
| SCHEMBL8440588 | 0.87 | ALDH1A1 (0.60) | ALDH1A1SGMS1PKMSMN1; SMN2MEN1 | |
| SCHEMBL8442977 | 0.87 | SGMS1 (0.55) | ALDH1A1SGMS1PKMMEN1KMT2A | |
| SCHEMBL8441169 | 0.85 | ALDH1A1 (0.63) | ALDH1A1SGMS1PKMPOLBSMN1; SMN2 | |
| SCHEMBL8438768 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SGMS1PKMSMN1; SMN2MEN1 | |
| SCHEMBL8437798 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SGMS1SMN1; SMN2NPSR1 | |
| SCHEMBL7918922 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SGMS1PKMPOLBSMN1; SMN2 | |
| SCHEMBL8440911 | 0.81 | NAMPT (0.48) | ALDH1A1PKMSMN1; SMN2CYP2C9TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |