Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.47 |
| ▸ | PPARA | Q07869 | 17/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662208 | 0.86 | ALDH1A1 (0.37) | PPARGPPARA | |
| SCHEMBL8445498 | 0.83 | PPARG (0.47) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL8440670 | 0.79 | PPARG (0.46) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL8444677 | 0.76 | PPARG (0.47) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL8445501 | 0.76 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL8472016 | 0.74 | PDE4A (0.36) | KDM4E | |
| SCHEMBL8471741 | 0.74 | KCNH2 (0.35) | — | |
| SCHEMBL9526779 | 0.71 | EHMT2 (0.46) | — | |
| SCHEMBL8421437 | 0.71 | PPARG (0.42) | PPARG | |
| SCHEMBL8500896 | 0.71 | KDM4E (0.46) | PPARGPPARAPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939445-A | ISOXAZOLIDINEDIONES COMPOUNDS AS HYPOGLYCEMIC AGENTS AND TREATMENT OF ARTERIOSCLEROSIS | JAPAN TOBACCO, INC. (JP) | 1999-08-17 | — | — | US | disclosed |
| US-5728720-A | HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; TREATMENT OF DIABETES | JAPAN TOBACCO INC. (JP) | 1998-03-17 | — | — | US | disclosed |