Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441450 | 1.00 | SOAT2 (0.46) | SOAT2ACAT1SOAT1LMNAPAX8 | |
| SCHEMBL9000782 | 0.80 | SOAT2 (0.59) | SOAT2ACAT1SOAT1LMNAPAX8 | |
| SCHEMBL8419057 | 0.80 | SOAT2 (0.59) | SOAT2ACAT1SOAT1LMNAPAX8 | |
| SCHEMBL8439085 | 0.79 | TBXA2R (0.43) | LMNAPAX8ALDH1A1POLBMAPT | |
| SCHEMBL8441453 | 0.76 | MEN1 (0.48) | ALDH1A1KMT2APTPN1 | |
| SCHEMBL8440775 | 0.76 | MEN1 (0.48) | ALDH1A1KMT2APTPN1 | |
| SCHEMBL14602835 | 0.75 | ALDH1A1 (0.63) | SOAT2SOAT1ALDH1A1HTTPTPN1 | |
| SCHEMBL8441161 | 0.71 | TBXA2R (0.52) | LMNAALDH1A1POLBMAPTHTT | |
| SCHEMBL8438050 | 0.71 | ALDH1A1 (0.59) | LMNAALDH1A1POLBMAPTHTT | |
| SCHEMBL8441437 | 0.71 | TBXA2R (0.52) | LMNAALDH1A1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |