SCHEMBL8440784

SCHEMBL8440784

COC(=O)C1(C)CCC(O)CC1C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 2/20 0.41
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974790 0.79 APLNR (0.38) PAX8MEN1POLBKMT2AALDH1A1
SCHEMBL24174938 0.79 PAX8 (0.38) PAX8MEN1POLBKMT2AHSD11B1
SCHEMBL974789 0.79 PAX8 (0.38) PAX8MEN1POLBKMT2AALDH1A1
SCHEMBL15423564 0.76
SCHEMBL27995063 0.76
SCHEMBL10955792 0.76
SCHEMBL3978516 0.74 MAPT (0.42) MEN1POLBKMT2AALDH1A1L3MBTL1
SCHEMBL19880954 0.73 PAX8 (0.34) PAX8MEN1POLBKMT2AALDH1A1
SCHEMBL24983263 0.72 PAX8 (0.38) PAX8MEN1POLBKMT2A
SCHEMBL29646187 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0922690-A1 PROCESS FOR THE PREPARATION OF CYCLOHEXANEDIMETHANOL NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-06-16 EP disclosed