Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974789 | 0.87 | PAX8 (0.38) | PAX8CYP1A2POLBMEN1KMT2A | |
| SCHEMBL151899 | 0.82 | GRM2 (0.44) | APLNRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL6944495 | 0.82 | GRM2 (0.44) | APLNRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL353161 | 0.82 | GRM2 (0.44) | APLNRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL6944486 | 0.82 | GRM2 (0.44) | APLNRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL353162 | 0.82 | GRM2 (0.44) | APLNRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL9134965 | 0.82 | GRM2 (0.44) | APLNRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL8440784 | 0.79 | PAX8 (0.41) | PAX8POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL15967434 | 0.77 | APLNR (0.31) | APLNR | |
| SCHEMBL8734101 | 0.74 | GRM2 (0.35) | APLNRGRM2GRM3GRM4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981018-B | Method for separating fumaric acid and other secondary components during the production of maleic anhydride | BASF SE | 2013-07-24 | — | — | CN | disclosed |
| US-8476463-B2 | Process for separating off fumaric acid and other minor components during the production of maleic anhydride | BASF SE (DE) | 2013-07-02 | — | — | US | disclosed |
| CN-101981018-A | Method for separating fumaric acid and other secondary components during the production of maleic anhydride | BASF SE | 2011-02-23 | — | — | CN | disclosed |
| US-20110021789-A1 | PROCESS FOR SEPARATING OFF FUMARIC ACID AND OTHER MINOR COMPONENTS DURING THE PRODUCTION OF MALEIC ANHYDRIDE | BASF SE (DE) | 2011-01-27 | — | — | US | disclosed |
| US-20090143601-A1 | METHOD FOR PREVENTING FUMARIC ACID DEPOSITS IN THE PRODUCTION OF MALEIC ACID ANHYDRIDE | BASF SE (DE) | 2009-06-04 | — | — | US | disclosed |