Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440267 | 0.94 | TMEM97 (0.43) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL8439277 | 0.90 | PDE4B (0.43) | MAPK1HTTALDH1A1MAPTPOLB | |
| SCHEMBL8440765 | 0.85 | MAPK1 (0.45) | MAPK1ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL8664616 | 0.82 | MAPK1 (0.47) | MAPK1HTTTSHRPRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL8817606 | 0.82 | HRH3 (0.40) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8444315 | 0.80 | CA12 (0.42) | HTTALDH1A1MAPTLMNAPOLB | |
| Hydrochloric Acid SCHEMBL8440407 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1LMNAPOLBNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8440293 | 0.76 | APP (0.53) | ALDH1A1LMNAPOLBNPSR1HSD17B10 | |
| SCHEMBL8440888 | 0.75 | LMNA (0.53) | TSHRALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL7995581 | 0.75 | MCHR1 (0.46) | MAPK1TSHRALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |