Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995581 | 0.94 | MCHR1 (0.46) | MAPK1TSHRALDH1A1MCHR1POLB | |
| SCHEMBL8007800 | 0.90 | ADORA1 (0.47) | HTTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL8005080 | 0.85 | KMT2A (0.51) | MAPK1ALDH1A1LMNAHPGDADORA1 | |
| Hydrochloric Acid SCHEMBL7995813 | 0.84 | KMT2A (0.50) | MAPK1ALDH1A1LMNAHPGDADORA1 | |
| SCHEMBL8440805 | 0.82 | MAPK1 (0.42) | MAPK1HTTTSHRALDH1A1PRMT5 | |
| SCHEMBL7996045 | 0.79 | LMNA (0.45) | MAPK1TSHRALDH1A1MCHR1POLB | |
| Hydrochloric Acid SCHEMBL7996052 | 0.78 | LMNA (0.46) | MAPK1TSHRALDH1A1MCHR1POLB | |
| SCHEMBL7995563 | 0.78 | LMNA (0.61) | MAPK1ALDH1A1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL8007343 | 0.75 | ALDH1A1 (0.58) | ALDH1A1POLBKDM4ELMNANPSR1 | |
| SCHEMBL8440267 | 0.75 | TMEM97 (0.43) | MAPK1TSHRALDH1A1MCHR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876338-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025310-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |