Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FHIT | P49789 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669568 | 0.90 | ALDH1A1 (0.41) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11632785 | 0.86 | GAA (0.43) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11634990 | 0.83 | ALDH1A1 (0.39) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11635514 | 0.82 | ALDH1A1 (0.39) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8440916 | 0.79 | MAPK1 (0.47) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11632117 | 0.79 | MAPT (0.38) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11634168 | 0.79 | MAPT (0.34) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11633572 | 0.78 | NPSR1 (0.38) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11636776 | 0.78 | TSHR (0.38) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL26601814 | 0.78 | ALDH1A1 (0.43) | GAAALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142676-A1 | Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules | CHEE GAIK-LEAN (CA) | 2012-06-07 | — | — | US | disclosed |
| WO-2012024083-A1 | OXATHIAZINE AND DITHIINE OXIDES AS INHIBITORS OF SULFHYDRYL-DEPENDENT BIOMOLECULES | CHEMTURA CORPORATION (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142676-A1 | Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules | HPGDS, SHMT1, QSOX1 | GAA 2499/4885ALDH1A1 1163/4885MAPT 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.