Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.62 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360592 | 0.79 | KMT2A (0.71) | TLR7BRAFGRM4MAPTCES1 | |
| SCHEMBL28290705 | 0.79 | KMT2A (0.71) | TLR7BRAFGRM4MAPTCES1 | |
| SCHEMBL27711530 | 0.75 | HDAC1 (0.52) | TLR7GRM4KDM4EMAPT | |
| SCHEMBL28871752 | 0.75 | TLR7 (0.70) | TLR7BRAFGRM4MAPTCES1 | |
| SCHEMBL27930549 | 0.75 | PTGS1 (0.56) | TLR7GRM4KDM4EMAPTKMT2A | |
| SCHEMBL28102321 | 0.73 | TLR7 (0.56) | TLR7GRM4KDM4EMAPTCES1 | |
| SCHEMBL17895178 | 0.73 | TLR7 (0.60) | TLR7BRAFGRM4CES1KMT2A | |
| SCHEMBL30416650 | 0.73 | HDAC3 (0.63) | TLR7BRAFGRM4KDM4EMAPT | |
| SCHEMBL28162063 | 0.72 | TLR7 (0.54) | TLR7GRM4KDM4EKMT2A | |
| SCHEMBL3879401 | 0.71 | KDM4E (0.51) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5900484-A | FROM HETEROAROMATIC HALOGEN COMPOUNDS AND AROMATIC AMINES AND CARBON MONOXIDE WITH PALLADIUM PHOSPHINE COMPLEX | LONZA AG (CH) | 1999-05-04 | — | — | US | disclosed |