Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443201 | 0.95 | TDP1 (0.44) | DRD2DRD3CYP2D6CYP2C19 | |
| SCHEMBL8441419 | 0.90 | LMNA (0.47) | CYP2D6CYP2C19HRH3KCNH2 | |
| SCHEMBL8439870 | 0.85 | LMNA (0.47) | — | |
| SCHEMBL8669339 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL8443200 | 0.83 | KMT2A (0.42) | DRD3KCNH2ADRA1A | |
| SCHEMBL8672723 | 0.82 | MEN1 (0.38) | — | |
| SCHEMBL8442151 | 0.81 | MEN1 (0.44) | KCNH2 | |
| SCHEMBL8522391 | 0.81 | POLB (0.45) | CYP2D6CYP2C19HRH3KCNH2 | |
| SCHEMBL8550349 | 0.81 | KDM4E (0.42) | — | |
| SCHEMBL8438243 | 0.80 | CHRNB4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |