Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441419 | 0.95 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL8443201 | 0.90 | TDP1 (0.44) | SMN1; SMN2PDE2A | |
| SCHEMBL8441860 | 0.85 | DRD2 (0.46) | — | |
| SCHEMBL8522391 | 0.84 | POLB (0.45) | LMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8441358 | 0.83 | SYK (0.45) | LMNAPDE2ASIGMAR1MKNK1ALDH1A1 | |
| SCHEMBL8672723 | 0.81 | MEN1 (0.38) | LMNASMN1; SMN2PDE2APOLBALDH1A1 | |
| SCHEMBL8443200 | 0.81 | KMT2A (0.42) | LMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8669339 | 0.81 | MEN1 (0.39) | LMNASMN1; SMN2PDE2APOLBALDH1A1 | |
| SCHEMBL8442151 | 0.80 | MEN1 (0.44) | POLBMKNK1 | |
| SCHEMBL8550349 | 0.80 | KDM4E (0.42) | LMNASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |