Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956840 | 1.00 | PKM (0.67) | PKMMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7956839 | 1.00 | PKM (0.67) | PKMMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13333443 | 0.90 | PKM (0.67) | PKMMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17520646 | 0.84 | NPSR1 (0.56) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3845771 | 0.84 | PKM (0.74) | PKMMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3849942 | 0.83 | GABRA1 (0.53) | PKMKDM4E | |
| SCHEMBL3849939 | 0.83 | GABRA1 (0.53) | PKMKDM4E | |
| SCHEMBL8433873 | 0.83 | GABRA1 (0.53) | PKMKDM4E | |
| SCHEMBL8862546 | 0.83 | PKM (0.58) | PKMMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8862543 | 0.83 | PKM (0.58) | PKMMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964835-A1 | Derivatives of psammaplin A, a method for their synthesis and their use for the prevention or treatment of cancer | Centre National de la Recherche Scientifique (FR) | 2008-09-03 | — | — | EP | disclosed |