Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849942 | 1.00 | GABRA1 (0.53) | GABRA1GABRB1GABRA3GABRB2MTNR1A | |
| SCHEMBL3849939 | 1.00 | GABRA1 (0.53) | GABRA1GABRB1GABRA3GABRB2MTNR1A | |
| SCHEMBL13333453 | 0.91 | GABRA1 (0.53) | GABRA1GABRB1GABRA3GABRB2MTNR1A | |
| SCHEMBL17520646 | 0.87 | NPSR1 (0.56) | PKMHTR2AKDM4ESLC6A4IDO1 | |
| SCHEMBL24012125 | 0.85 | KDM4E (0.62) | MTNR1AMTNR1BGPR84HTR2ATRPM8 | |
| SCHEMBL17500189 | 0.85 | KDM4E (0.62) | MTNR1AMTNR1BGPR84HTR2ATRPM8 | |
| SCHEMBL7956840 | 0.83 | PKM (0.67) | PKMKDM4E | |
| SCHEMBL7956839 | 0.83 | PKM (0.67) | PKMKDM4E | |
| SCHEMBL8442871 | 0.83 | PKM (0.67) | PKMKDM4E | |
| SCHEMBL3703101 | 0.83 | PKM (0.67) | GABRA1GABRB1GABRA3GABRB2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964835-A1 | Derivatives of psammaplin A, a method for their synthesis and their use for the prevention or treatment of cancer | Centre National de la Recherche Scientifique (FR) | 2008-09-03 | — | — | EP | disclosed |