Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442024 | 0.84 | NR1H2 (0.32) | MMP1 | |
| SCHEMBL8441581 | 0.79 | NR1H2 (0.34) | — | |
| SCHEMBL3885758 | 0.79 | MAOA (0.35) | — | |
| SCHEMBL8444000 | 0.78 | MMP1 (0.33) | MMP1 | |
| SCHEMBL8443598 | 0.77 | LIPG (0.30) | — | |
| SCHEMBL8440791 | 0.75 | MMP1 (0.32) | MMP1 | |
| SCHEMBL8441769 | 0.74 | MAPT (0.37) | MMP1 | |
| SCHEMBL5692425 | 0.71 | MEN1 (0.31) | — | |
| SCHEMBL8439849 | 0.70 | — | — | |
| SCHEMBL8444631 | 0.70 | MDM4 (0.33) | MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962435-A | ANTICHOLESTEROL AGENT | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| CN-1029615-C | Novel 2,6-Di-alkyl-4-silyl-phenols as antiatherosclerotic agents | MERRELL DOW PHARMA (US) | 1995-08-30 | — | — | CN | disclosed |
| CN-1057843-A | New 2 as antiatherosclerotic, 6-two-alkyl-4-silyl-phenols | MERRELL DOW PHARMA (US) | 1992-01-15 | — | — | CN | disclosed |