Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517241 | 0.80 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL8442028 | 0.80 | GABRA1 (0.36) | P4HBGABRA1GABRB2 | |
| SCHEMBL7526911 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL8441588 | 0.78 | P4HB (0.34) | P4HBELANECTSG | |
| SCHEMBL8443601 | 0.76 | BID (0.36) | P4HBELANECTSG | |
| SCHEMBL7526671 | 0.76 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL8440795 | 0.74 | GABRA1 (0.41) | P4HBGABRA1GABRB2 | |
| SCHEMBL8441767 | 0.72 | TRPA1 (0.43) | P4HB | |
| SCHEMBL258656 | 0.72 | GABRA1 (0.63) | P4HBGABRA1GABRB2ELANECTSG | |
| SCHEMBL8885071 | 0.71 | GABRA1 (0.42) | GABRA1GABRB2ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962435-A | ANTICHOLESTEROL AGENT | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-05 | — | — | US | disclosed |