Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876723 | 0.87 | NOTUM (0.38) | NOTUMCYP11B1CYP11B2ALDH1A1NPSR1 | |
| Phenylboronic Acid SCHEMBL988758 | 0.87 | CA4 (0.44) | NOTUMCYP11B1CYP11B2ALDH1A1NPSR1 | |
| SCHEMBL16975525 | 0.85 | KIF11 (0.37) | NOTUMCYP11B1CYP11B2ALDH1A1NPSR1 | |
| SCHEMBL2360873 | 0.83 | KCNN4 (0.57) | NOTUMCYP11B1CYP11B2ALDH1A1NPSR1 | |
| SCHEMBL8987731 | 0.80 | NOTUM (0.42) | NOTUMCYP11B1CYP11B2ALDH1A1NPSR1 | |
| SCHEMBL28835340 | 0.80 | TPMT (0.41) | NOTUMALDH1A1RAB9AKMT2AMAPT | |
| SCHEMBL29280760 | 0.80 | ALDH1A1 (0.41) | NOTUMCYP11B1CYP11B2ALDH1A1NPSR1 | |
| SCHEMBL3370410 | 0.75 | TAAR1 (0.39) | NOTUMALDH1A1NPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL1132120 | 0.74 | ALDH1A1 (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL7796676 | 0.71 | CYP11B1 (0.46) | NOTUMCYP11B1CYP11B2NPSR1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221603-A | Preparation method of valsartan | 南京法恩化学有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118108679-A | Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole | 南京法恩化学有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-115322175-A | Synthesis process of candesartan | 安徽美诺华药物化学有限公司 | 2022-11-11 | — | — | CN | claimed |
| EP-2576575-B1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | UNIV FRASER SIMON (CA) | 2018-09-05 | — | — | EP | claimed |
| US-9611284-B2 | Prostaglandin-bisphosphonate conjugate compounds, methods of making same, and uses thereof | SIMON FRASER UNIVERSITY (CA) | 2017-04-04 | — | — | US | claimed |
| US-20130157984-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2013-06-20 | — | — | US | claimed |
| EP-2576575-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | Simon Fraser University (CA) | 2013-04-10 | — | — | EP | claimed |
| WO-2011147034-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2011-12-01 | — | — | WO | claimed |
| CN-1668612-A | New synthesis method of irbesartan | TEVA PHARMA (IL) | 2005-09-14 | — | — | CN | claimed |
| EP-0324377-B1 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | DU PONT (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0479903-B1 | SUBSTITUTED IMIDAZOLES USEFUL AS ANGIOTENSIN II BLOCKERS | DU PONT (US) | 1996-02-21 | — | — | EP | claimed |
| EP-0253310-B1 | Angiotensin II receptor blocking imidazoles | DU PONT (US) | 1994-10-26 | — | — | EP | claimed |
| CN-1088202-A | Benzoglyoxaline contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-06-22 | — | — | CN | claimed |
| EP-0479892-A1 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0479903-A1 | SUBSTITUTED IMIDAZOLES. | DU PONT (US) | 1992-04-15 | — | — | EP | claimed |
| WO-1991000277-A1 | SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-10 | — | — | WO | claimed |
| WO-1991000281-A2 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-10 | — | — | WO | claimed |
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | claimed |
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | claimed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157984-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | PTGES, PTGFR, PTGIS | NOTUM 297/4885CYP11B1 328/4885CYP11B2 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.