SCHEMBL8443095

SCHEMBL8443095

CCCCCCCCCCCCCCCC(=O)Nc1ccc(OCC)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.69
L3MBTL1 Q9Y468 2/20 0.68
GAA P10253 1/20 0.68
HTT P42858 1/20 0.67
CNR1 P21554 1/20 0.65
TSHR P16473 2/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
LMNA P02545 2/20 0.59
CYP1A2 P05177 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MAPT P10636 2/20 0.58
ALDH1A1 P00352 2/20 0.58
MAPK1 P28482 1/20 0.58
HDAC3 O15379 1/20 0.58
HDAC4 P56524 1/20 0.58
HDAC1 Q13547 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HDAC10 Q969S8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11642285 1.00 POLB (0.69) POLBL3MBTL1GAAHTTCNR1
SCHEMBL10652806 1.00 POLB (0.69) POLBL3MBTL1GAAHTTCNR1
SCHEMBL8986265 0.94 POLB (0.73) POLBL3MBTL1GAAHTTTSHR
SCHEMBL18259440 0.88 CNR1 (0.68) L3MBTL1GAACNR1LMNAHDAC3
SCHEMBL9842944 0.87 POLB (0.77) POLBGAAHTTTSHRMEN1
SCHEMBL9858666 0.87 ENPP2 (0.71) POLBL3MBTL1CNR1LMNAALDH1A1
SCHEMBL675018 0.87 ENPP2 (0.71) POLBL3MBTL1CNR1LMNAALDH1A1
SCHEMBL9510547 0.87 ENPP2 (0.71) POLBL3MBTL1CNR1LMNAALDH1A1
SCHEMBL27686977 0.86 ALDH1A1 (0.65) POLBGAAMEN1KMT2ALMNA
SCHEMBL12215287 0.86 L3MBTL1 (0.84) L3MBTL1GAAHTTCNR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929557-A2 (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES CLARION PHARMACEUTICALS, INC. (US) 1999-07-21 EP disclosed
WO-1998014454-A2 (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES CLARION PHARMACEUTICALS, INC. (US) 1998-04-09 WO disclosed
US-5661138-A ANTIINFLAMMATORY AGENTS; THE ALKYL GROUP OF THE N-ACYLAMINO GROUP HAVING 9-23 CARBON ATOMS CLARION PHARMACEUTICAL, INC. (US) 1997-08-26 US disclosed