Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115396 | 0.77 | PTGS1 (0.44) | DHODHDAOKMOBCAT2 | |
| SCHEMBL2461016 | 0.74 | BCAT2 (0.47) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14397797 | 0.74 | GPR35 (0.40) | ALDH1A1KDM4EL3MBTL1MEN1NPC1 | |
| SCHEMBL9696347 | 0.73 | PRKDC (0.41) | ALDH1A1L3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8443923 | 0.72 | DHODH (0.36) | DHODHDAOKMOBCAT2 | |
| SCHEMBL8444035 | 0.72 | ERN1 (0.56) | ERN1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL1829790 | 0.72 | PTGS2 (0.45) | ERN1ALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL14397460 | 0.71 | MEN1 (0.38) | ALDH1A1KDM4ETDP1POLBMEN1 | |
| SCHEMBL14398058 | 0.70 | KDM4E (0.46) | ERN1ALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL16399919 | 0.70 | CNR1 (0.39) | L3MBTL1MEN1KMT2APRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |