Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748918 | 0.76 | ALDH1A1 (0.45) | LMNAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL7748913 | 0.76 | ALDH1A1 (0.45) | LMNAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL7393110 | 0.68 | KMT2A (0.50) | ALDH1A1TDP1DPP4KMT2AMEN1 | |
| SCHEMBL8305851 | 0.67 | KMT2A (0.46) | LMNAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL8305853 | 0.67 | KMT2A (0.46) | LMNAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL4679636 | 0.67 | ATM (0.55) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL1731885 | 0.66 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8439823 | 0.66 | ATM (0.54) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL8307349 | 0.66 | KMT2A (0.40) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4226418 | 0.65 | KMT2A (0.49) | LMNAALDH1A1KDM4ETDP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952842-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-11-03 | — | — | EP | claimed |
| WO-1997038664-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | claimed |