Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 4/20 | 0.35 |
| ▸ | CPB1 | P15086 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875144 | 0.86 | CPB2 (0.40) | CPB2QPCTCPB1KDM1A | |
| SCHEMBL8447250 | 0.84 | CPB2 (0.37) | CPB2QPCTCPB1KDM1AHDAC6 | |
| SCHEMBL7877070 | 0.82 | ESRRG (0.41) | KDM4EKDM1AHDAC6GAA | |
| SCHEMBL8446127 | 0.79 | QPCT (0.38) | CPB2KDM4EL3MBTL1QPCTCPB1 | |
| SCHEMBL7868627 | 0.77 | MAPT (0.47) | KDM4EGAA | |
| SCHEMBL7868567 | 0.76 | NOS3 (0.42) | KDM1AHDAC6GAA | |
| SCHEMBL8443379 | 0.75 | CYP11B1 (0.52) | QPCT | |
| SCHEMBL8444492 | 0.74 | QPCTL (0.37) | CPB2KDM4EL3MBTL1QPCT | |
| SCHEMBL5656588 | 0.68 | CPB2 (0.48) | CPB2KDM4EL3MBTL1CPB1 | |
| SCHEMBL27998267 | 0.67 | NAAA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |