SCHEMBL8444150

SCHEMBL8444150

CCC(CC)C(=O)OC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 5/20 0.40
LMNA P02545 4/20 0.36
TSHR P16473 3/20 0.36
MAPT P10636 2/20 0.36
ALOX15 P16050 1/20 0.36
CYP2D6 P10635 4/20 0.35
CYP1A2 P05177 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HIF1A Q16665 3/20 0.33
CYP2C19 P33261 2/20 0.33
GMNN O75496 1/20 0.33
ESR1 P03372 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX12 P18054 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27723630 0.85 ALDH1A1 (0.48) ALDH1A1KDM4ELMNATSHRMAPT
Citric Acid SCHEMBL21855097 0.83 ALDH1A1 (0.54) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL27557036 0.83 ALDH1A1 (0.54) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL28887877 0.82 HSPD1 (0.47) ALDH1A1LMNAMEN1KMT2ABLM
SCHEMBL1362574 0.81 ALDH1A1 (0.52) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL11699991 0.81 TSHR (0.40) ALDH1A1KDM4ETSHRMAPTMEN1
SCHEMBL27675763 0.81 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT
Citric Acid SCHEMBL6429240 0.80 ALDH1A1 (0.60) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL437151 0.80 ALDH1A1 (0.60) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL2394722 0.80 ALDH1A1 (0.50) ALDH1A1KDM4ELMNATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116829643-A (meth) acrylic resin composition, inorganic fine particle dispersion slurry composition, and inorganic fine particle dispersion molded article 积水化学工业株式会社 2023-09-29 CN disclosed
EP-0654038-B1 CONTROLLED RELEASE PHARMACEUTICAL FORMULATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND METHODS OF USE DUNN JAMES M (US) 1999-11-10 EP disclosed
US-5681581-A Controlled release pharmaceutical formulations of 3'-azido-3'-deoxythymidine and methods of use DUNN JAMES M (US) 1997-10-28 US disclosed
EP-0654038-A4 CONTROLLED RELEASE PHARMACEUTICAL FORMULATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND METHODS OF USE. DUNN JAMES M (US) 1996-02-28 EP disclosed
EP-0654038-A1 CONTROLLED RELEASE PHARMACEUTICAL FORMULATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND METHODS OF USE Dunn, James M. (US) 1995-05-24 EP disclosed
WO-1994003471-A1 CONTROLLED RELEASE PHARMACEUTICAL FORMULATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND METHODS OF USE VEREX LABORATORIES, INC. (US) 1994-02-17 WO disclosed