Sugi Predict

Sugi Predict / Compounds / SCHEMBL437151

SCHEMBL437151

SCHEMBL437151

CCC(=O)OC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.60
▸ KDM4E B2RXH2 7/20 0.42
▸ LMNA P02545 6/20 0.42
▸ CYP2D6 P10635 5/20 0.42
▸ CYP1A2 P05177 4/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ TSHR P16473 3/20 0.41
▸ MAPT P10636 3/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ HIF1A Q16665 3/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ TP53 P04637 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ GMNN O75496 1/20 0.39
▸ ESR1 P03372 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ ALOX12 P18054 1/20 0.39
▸ NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL6429240 1.00 ALDH1A1 (0.60) ALDH1A1KDM4ELMNACYP2D6CYP1A2
Propionic Acid SCHEMBL27572376 0.98 ALDH1A1 (0.58) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL27997500 0.98 ALDH1A1 (0.58) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL9615611 0.98 ALDH1A1 (0.58) ALDH1A1KDM4ELMNACYP2D6CYP1A2
Malonic Acid SCHEMBL28763621 0.94 ALDH1A1 (0.54) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL27572383 0.92 ALDH1A1 (0.71) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL27588804 0.92 ALDH1A1 (0.71) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL934375 0.92 ALDH1A1 (0.71) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL144692 0.92 ALDH1A1 (0.71) ALDH1A1KDM4ELMNACYP2D6CYP1A2
SCHEMBL9325416 0.90 ALDH1A1 (0.68) ALDH1A1KDM4ELMNACYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108479414-A Hollow fiber polymer membrane, preparation method and application thereof in brine refining 南京工业大学 2018-09-04 — — CN claimed
CN-108057346-A High-flux polymer separation membrane, preparation method, diluent composition and application 南京工业大学 2018-05-22 — — CN claimed
US-20150273066-A1 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS RAMSCOR INC (US) 2015-10-01 — — US claimed
US-20140329785-A1 Conveniently Injectable or Implantable Sustained-Release Antioxidant Formulations for Therapies of Ocular Maladies or Cancer RAMSCOR, INC. (US) 2014-11-06 — — US claimed
US-20140140992-A1 Sustained Release Formulations for Delivery of Proteins to the Eye and Methods of Preparing Same ICON BIOSCIENCE, INC. (US) 2014-05-22 — — US claimed
EP-2717914-A2 SUSTAINED RELEASE FORMULATIONS FOR DELIVERY OF PROTEINS TO THE EYE AND METHODS OF PREPARING SAME Ramscor, Inc. (US) 2014-04-16 — — EP claimed
WO-2013036309-A2 SUSTAINED RELEASE FORMULATIONS FOR DELIVERY OF PROTEINS TO THE EYE AND METHODS OF PREPARING SAME WONG VERNON G (US) 2013-03-14 — — WO claimed
US-20090148414-A1 Novel Composition to Improve Gut Health and Animal Performance and Methods of Making the Same BIOATLANTIS LIMITED (IE) 2009-06-11 — — US claimed
US-20090136445-A1 SUSTAINED RELEASE EYE DROP FORMULATIONS RAMSCOR, INC. 2009-05-28 — — US claimed
US-20080038316-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2008-02-14 — — US claimed
EP-1126838-A4 NITROSATED AND NITROSYLATED NONSTEROIDAL ANTIINFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED INC (US) 2005-02-16 — — EP claimed
US-20030207919-A1 Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use NICOX S.A. (FR) 2003-11-06 — — US claimed
US-6593347-B2 Especially a nitrosated and/or nitrosylated arylpropionic acid, arylacetic acid, enolic anilide or an oxicam NITROMED, INC. 2003-07-15 — — US claimed
JP-2002528495-A — — 2002-09-03 — — JP claimed
US-20020016322-A1 Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositons and methods of use NICOX S.A. (FR) 2002-02-07 — — US claimed
EP-1126838-A1 NITROSATED AND NITROSYLATED NONSTEROIDAL ANTIINFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2001-08-29 — — EP claimed
WO-2000025776-A1 NITROSATED AND NITROSYLATED NONSTEROIDAL ANTIINFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2000-05-11 — — WO claimed
CN-107417819-B Solid catalyst component for olefin polymerization, catalyst and application thereof 北京利和知信科技有限公司 2021-11-16 — — CN disclosed
US-5491050-A DEVELOPMENT IN PRESENCE OF 1-PHENYLPYRAZOLIDONE-3-ONE EASTMAN KODAK COMPANY (US) 1996-02-13 — — US disclosed
US-5290353-A Vaterite and production method LHOIST RECHERCHE ET DEVELOPPEMENT S.A. (BE) 1994-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016322-A1 Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositons and methods of use NOS2, NOS3, NOS1 ALDH1A1 1076/4885KDM4E 4320/4885LMNA 2101/4885
US-20030207919-A1 Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use NOS2, NOS1, NOS3 ALDH1A1 360/4885KDM4E 3946/4885LMNA 2283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.