Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EIF4A3 | P38919 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12777647 | 0.77 | KDM4E (0.55) | NFKB1ALOX15BLMSMN1; SMN2KDM4E | |
| SCHEMBL282290 | 0.76 | GPR35 (0.48) | NFKB1ALOX15BLMSMN1; SMN2KDM4E | |
| SCHEMBL10879188 | 0.76 | NOTUM (0.55) | NFKB1ALOX15BLMSMN1; SMN2KDM4E | |
| SCHEMBL31386787 | 0.75 | ALDH1A1 (0.50) | ALOX15SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL14857846 | 0.74 | ALOX15 (0.52) | NFKB1ALOX15BLMSMN1; SMN2KDM4E | |
| SCHEMBL3117809 | 0.74 | ALOX15 (0.46) | NFKB1ALOX15BLMSMN1; SMN2KDM4E | |
| SCHEMBL508616 | 0.74 | GRIN1 (0.47) | NFKB1ALOX15BLMSMN1; SMN2EIF4A3 | |
| SCHEMBL18725471 | 0.72 | GPR35 (0.59) | NFKB1ALOX15BLMSMN1; SMN2KDM4E | |
| SCHEMBL23147766 | 0.71 | EIF4A3 (0.64) | NFKB1EIF4A3KDM4EHPGDHSD17B10 | |
| SCHEMBL20159038 | 0.71 | ALOX15 (0.43) | NFKB1ALOX15BLMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255697-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2024-12-19 | — | — | WO | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |