Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.61 |
| ▸ | TK2 | O00142 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444516 | 0.87 | TYMP (0.49) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL11252365 | 0.85 | LMNA (0.56) | TYMPTK2MAPTCYP2C9KMT2A | |
| SCHEMBL23897613 | 0.79 | MAPK1 (0.51) | TYMPMAPK1TK1HPGD | |
| SCHEMBL17583277 | 0.79 | TYMP (0.63) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL17583278 | 0.78 | TYMP (0.54) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL3854773 | 0.76 | TYMP (1.00) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL6153435 | 0.76 | TYMP (0.66) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL24322118 | 0.75 | TYMP (0.54) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL30903369 | 0.74 | TYMP (0.60) | TYMPTK2MAPK1TK1HPGD | |
| SCHEMBL23453029 | 0.74 | TYMP (0.59) | TYMPTK2MAPK1TK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766691-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035304-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1995-12-28 | — | — | WO | disclosed |