Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351380 | 0.84 | POLB (0.74) | POLBALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL10359739 | 0.76 | POLB (0.57) | POLBALDH1A1MAPTCA1CA2 | |
| SCHEMBL4539301 | 0.75 | DRD2 (0.73) | LMNADRD2TSHR | |
| SCHEMBL27463569 | 0.75 | POLB (0.64) | POLBALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL4875267 | 0.74 | ALDH1A1 (0.79) | POLBALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9513528 | 0.74 | CA1 (0.54) | POLBLMNACA1CA2CA7 | |
| SCHEMBL9516076 | 0.74 | HRH3 (0.47) | POLBALDH1A1MAPTKDM4ECA1 | |
| SCHEMBL3709528 | 0.74 | MAPT (0.68) | POLBALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL6301694 | 0.73 | MAPT (0.72) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19851992 | 0.73 | TSHR (0.64) | POLBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395312-B1 | Piperazine derivatives | WYETH JOHN & BROTHER LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-3910916-A | 1-(4-Methanesulfonyl phenacyl)-4-phenyl piperazine | SPOFA VEREINIGTE PHARMA WERKE | 1975-10-07 | — | — | US | disclosed |