Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489460 | 0.90 | DPP8 (0.37) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL8448802 | 0.90 | DPP8 (0.37) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL8448807 | 0.90 | DPP8 (0.37) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL8444908 | 0.90 | TPSAB1 (0.39) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL8447430 | 0.90 | TPSAB1 (0.39) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL7453533 | 0.87 | CCR2 (0.36) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL7453530 | 0.87 | CCR2 (0.36) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL7453675 | 0.86 | ALDH1A1 (0.36) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL7453669 | 0.86 | ALDH1A1 (0.36) | DPP8DPP9TPSAB1TPSD1TPSG1 | |
| SCHEMBL8448820 | 0.86 | GRIN2B (0.34) | DPP8DPP9GRIN2BALDH1A1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |