Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493680 | 0.83 | TSHR (0.46) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL5498913 | 0.79 | CA1 (0.37) | MAPTMEN1KMT2ACA1CA2 | |
| SCHEMBL8300688 | 0.75 | MAPT (0.45) | MAPTMEN1KMT2ATP53PDE4A | |
| SCHEMBL9242186 | 0.70 | KMO (0.40) | KMOABL1TP53GRIN2B | |
| SCHEMBL8300862 | 0.70 | PTGS1 (0.33) | KMOKDM4CFFAR1PTGS1PTGS2 | |
| SCHEMBL8299027 | 0.69 | MAPT (0.42) | MAPTKMOMEN1KMT2ATP53 | |
| SCHEMBL9247381 | 0.66 | FFAR1 (0.40) | KMOFFAR1KCNH2PTGS1PTGS2 | |
| SCHEMBL9248310 | 0.64 | NPC1 (0.37) | KMOKDM4CKCNH2PDE4D | |
| SCHEMBL9243146 | 0.64 | KDM4E (0.39) | KMOTP53 | |
| SCHEMBL9243119 | 0.63 | L3MBTL1 (0.41) | MAPTKMOTP53FFAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5855654-A | APPLYING (DIHYDRO)PYRIDAZINONE COMPOUND | ROHM AND HAAS COMPANY (US) | 1999-01-05 | — | — | US | claimed |
| EP-0856255-A2 | Pyridazinones as marine antifouling agents | ROHM AND HAAS COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |