Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243119 | 0.96 | L3MBTL1 (0.41) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9242186 | 0.93 | KMO (0.40) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9248905 | 0.89 | RAB9A (0.42) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9243735 | 0.85 | L3MBTL1 (0.43) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9247471 | 0.85 | NPC1 (0.41) | KDM4EKMOCHRNB2CHRNA4NPC1 | |
| SCHEMBL9243907 | 0.83 | FFAR1 (0.39) | EGFRPGK1 | |
| SCHEMBL9248764 | 0.82 | GRM5 (0.51) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9242098 | 0.82 | L3MBTL1 (0.47) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9249535 | 0.82 | RAB9A (0.40) | KDM4EALDH1A1HPGDKMOCHRNB2 | |
| SCHEMBL9245612 | 0.81 | NPC1 (0.44) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |