Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 8/20 | 0.73 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.73 |
| ▸ | RXRA | P19793 | 9/20 | 0.56 |
| ▸ | RARA | P10276 | 8/20 | 0.56 |
| ▸ | RARG | P13631 | 8/20 | 0.56 |
| ▸ | RARB | P10826 | 7/20 | 0.56 |
| ▸ | RXRB | P28702 | 6/20 | 0.56 |
| ▸ | RXRG | P48443 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22838114 | 0.84 | CYP26A1 (1.00) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL22838086 | 0.83 | CYP26A1 (1.00) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL7872150 | 0.82 | GLA (0.59) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL7872151 | 0.82 | GLA (0.59) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL7621355 | 0.81 | RARA (0.82) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL8336184 | 0.81 | CYP26A1 (0.56) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL7872160 | 0.78 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL7872162 | 0.78 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARARARARG | |
| SCHEMBL29177155 | 0.78 | HPGD (0.68) | MEN1KMT2AALDH1A1CYP1A2HPGD | |
| SCHEMBL7872280 | 0.78 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901462-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998034909-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-08-13 | — | — | WO | disclosed |