SCHEMBL8445095

SCHEMBL8445095

O=C1CN(CC#CI)C(=O)N1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.35
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2411663 0.78 CRBN (0.34) CRBN
SCHEMBL7519249 0.75 CRBN (0.38) CRBNEPHX2
SCHEMBL8999579 0.71 CRBN (0.46) CRBNEPHX2
SCHEMBL561442 0.67
SCHEMBL5235519 0.67
SCHEMBL11257635 0.66 CRBN (0.46) CRBNEPHX2
SCHEMBL11883745 0.64 CRBN (0.35) CRBNEPHX2
SCHEMBL17160566 0.64 CRBN (0.40) CRBNEPHX2
SCHEMBL8029439 0.64 CRBN (0.44) CRBNEPHX2
Formaldehyde SCHEMBL9059280 0.64 CRBN (0.39) CRBNEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346913-A Agricultural fungicides ROHM AND HAAS COMPANY (US) 1994-09-13 US claimed
JP-6056796-A None JP disclosed
US-6008244-A APPLYING ONTO OR INTO THE MARINE STRUCTURE TO INHIBIT GROWTH SUCH AS SOFT CORALS, TUNICATES, HYDROIDS, SPONGES, ANEMONES, BARNACLES, TUBEWORMS AND MOLLUSCS ROHM AND HAAS COMPANY (US) 1999-12-28 US disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0572191-B1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM & HAAS (US) 1996-09-04 EP disclosed
EP-0572191-B1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM & HAAS (US) 1996-09-04 EP disclosed
US-5346913-A Agricultural fungicides ROHM AND HAAS COMPANY (US) 1994-09-13 US disclosed
US-5346913-A Agricultural fungicides ROHM AND HAAS COMPANY (US) 1994-09-13 US disclosed
JP-H0656796-A N-IODOPROPARGYL HYDANTOIN COMPOUND, ITS COMPOSITION, ITS PRODUCTION AND ITS USE AS ANTIMICROBIAL AGENT ROHM & HAAS CO 1994-03-01 JP disclosed
EP-0572191-A1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM AND HAAS COMPANY (US) 1993-12-01 EP disclosed
EP-0572191-A1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM AND HAAS COMPANY (US) 1993-12-01 EP disclosed