Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443115 | 0.88 | EGFR (0.56) | PNLIPNAAAABL1PLK1EGFR | |
| SCHEMBL10970233 | 0.87 | BCL2L1 (0.61) | PNLIPNAAAABL1PLK1EGFR | |
| SCHEMBL17965862 | 0.82 | ALOX5 (0.54) | PNLIPNAAAEGFRSYKALOX5 | |
| SCHEMBL9484979 | 0.81 | ABL1 (0.55) | PNLIPNAAAABL1EGFRSYK | |
| SCHEMBL9768522 | 0.80 | ALDH1A1 (0.62) | EGFRPOLBHPGDALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL3632619 | 0.80 | BCL2L1 (0.57) | PNLIPPLK1BCL2L1MCL1PPARA | |
| SCHEMBL10759621 | 0.79 | KAT8 (0.58) | NAAAPLK1EGFRSYKALOX5 | |
| SCHEMBL11318599 | 0.79 | PLK1 (0.58) | NAAAABL1PLK1EGFRSYK | |
| SCHEMBL11307721 | 0.79 | PLK1 (0.58) | NAAAABL1PLK1EGFRSYK | |
| SCHEMBL11316566 | 0.79 | PLK1 (0.58) | NAAAABL1PLK1EGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929557-A2 | (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014454-A2 | (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1998-04-09 | — | — | WO | disclosed |
| US-5661138-A | ANTIINFLAMMATORY AGENTS; THE ALKYL GROUP OF THE N-ACYLAMINO GROUP HAVING 9-23 CARBON ATOMS | CLARION PHARMACEUTICAL, INC. (US) | 1997-08-26 | — | — | US | disclosed |