Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PNLIP | P16233 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 3/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965862 | 0.94 | ALOX5 (0.54) | EGFRALOX5PTGS2SYKNAAA | |
| SCHEMBL8445104 | 0.88 | PNLIP (0.55) | EGFRALOX5PTGS2SYKNAAA | |
| SCHEMBL10759621 | 0.88 | KAT8 (0.58) | EGFRALOX5PTGS2SYKNAAA | |
| SCHEMBL10767712 | 0.87 | KAT8 (0.56) | EGFRALOX5PTGS2SYKNAAA | |
| SCHEMBL9484979 | 0.81 | ABL1 (0.55) | EGFRALOX5PTGS2SYKNAAA | |
| SCHEMBL17614784 | 0.80 | ALDH1A1 (0.62) | EGFR | |
| SCHEMBL6581661 | 0.80 | ALDH1A1 (0.62) | EGFR | |
| SCHEMBL6579751 | 0.80 | ALDH1A1 (0.62) | EGFR | |
| SCHEMBL8445092 | 0.80 | ALDH1A1 (0.62) | EGFR | |
| SCHEMBL8844788 | 0.80 | ALDH1A1 (0.62) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929557-A2 | (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014454-A2 | (o-ACYL-p-N-ACYLAMINO-PHENYL)-O-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1998-04-09 | — | — | WO | disclosed |
| US-5661138-A | ANTIINFLAMMATORY AGENTS; THE ALKYL GROUP OF THE N-ACYLAMINO GROUP HAVING 9-23 CARBON ATOMS | CLARION PHARMACEUTICAL, INC. (US) | 1997-08-26 | — | — | US | disclosed |